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rINN: Nimodipine
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Nimodipine molecule
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Calcium channel blocker
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A Cochrane review showed that oral nimodipine was likely to be safer than iv nimodipine in subarachnoid haemorrhage and the iv preparation can be depreciated[1]. There is no other drug treatment of vasospasm that improves outcome[2].

Clinical Use


  • After aneurysmal subarachnoid haemorrhage




Clinical Issues


Cautions and Interactions

Side effects

Special advice



  1. Soppi V, Karamanakos PN, Koivisto T, Kurki MI, Vanninen R, Jaaskelainen JE, Rinne J. A Randomized Outcome Study of Enteral Versus Intravenous Nimodipine in 171 Patients after Acute Aneurysmal Subarachnoid Hemorrhage. World neurosurgery. Nov 1.(Link to article – subscription may be required.)
  2. Velat GJ, Kimball MM, Mocco JD, Hoh BL. Vasospasm after aneurysmal subarachnoid hemorrhage: review of randomized controlled trials and meta-analyses in the literature. World neurosurgery. Nov; 76(5):446-54.(Link to article – subscription may be required.)